DefyDiabetes – Volume 36 | Dec 2025

Journal Articles

GLP-1 Receptor Agonists and Risk of Optic Nerve or Vision- Threatening Events in Patients With Type 2 Diabetes or Cardiometabolic Diseases: A Meta-analysis of Randomized Controlled Trials

Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are established therapies for glycemic control in type 2 diabetes mellitus (T2DM) as well as weight loss (1,2). Obesity is recognized as a chronic disease and a key component of the cardiometabolic disease spectrum.

The New Obesity Treatment Landscape: Challenges and Opportunities to Promote Shared Decision-Making in People With Obesity and Type 2 Diabetes

Nearly 90% of adult patients with type 2 diabetes have overweight or obesity, defined according to body mass index (BMI) 25.0–29.9 or ≥30.0 kg/m², respectively (1). Treating obesity can improve symptom severity and prognosis among those with type 2 diabetes (2).