The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) compared several classes of glucose-lowering agents for people with type 2 diabetes (T2D) who were already being treated with lifestyle intervention and metformin
Lipodystrophy (LD) is a group of heterogeneous and rare disorders characterized by either generalized or partial lack of adipose tissue, depending on the type of LD (1,2). Familial partial lipodystrophy (FPLD) presents with partial loss of adipose tissue, insulin resistance, hypertriglyceridemia, and hepatic steatosis that result in metabolic comorbidities that are refractory to treatment.