DefyDiabetes – Volume 30 | Jun 2025

Journal Articles

A Critique of Measurement of Defective Insulin Secretion and Insulin Sensitivity as a Precision Approach to Gestational Diabetes

Precision medicine offers unique opportunities to revolutionise the diagnosis, management and long-term outlook for people with diabetes, but has yet to be widely used in gestational diabetes mellitus. The recent consensus report by Tobias et al as part of the ADA/EASD Precision Medicine in Diabetes Initiative outlined opportunities for precision approaches to improve GDM prevention, diagnosis, treatment and prognosis, suggesting that these should be key areas for focus.

Aetiology of Type 2 Diabetes: An Experimental Medicine Odyssey

Claude Bernard well deserves the title of Father of Experimental Medicine. He demonstrated that the processes within living tissues were explicable in scientific terms, challenging the universal belief that the functions of the body were controlled by a ‘vital force’. Claude Bernard pointed out that if an observation was thought about in the light of other knowledge then a hypothesis could be put forward to explain cause and effect.